Alfred M Sciuto Selected Research

VX (EDIM)

10/2018	Pulmonary toxicity following inhalation exposure to VX in anesthetized rats: Possible roles for compromised immunity and oxidative stress-induced lung injury.
6/2014	Acute pulmonary toxicity following inhalation exposure to aerosolized VX in anesthetized rats.
5/2007	Abdominal bloating and irritable bowel syndrome like symptoms following microinstillation inhalation exposure to chemical warfare nerve agent VX in guinea pigs.
3/2007	Medical countermeasure against respiratory toxicity and acute lung injury following inhalation exposure to chemical warfare nerve agent VX.
6/2006	Butyrylcholinesterase in guinea pig lung lavage: a novel biomarker to assess lung injury following inhalation exposure to nerve agent VX.
5/2006	Acute lung injury following inhalation exposure to nerve agent VX in guinea pigs.
1/2006	Development of a microinstillation model of inhalation exposure to assess lung injury following exposure to toxic chemicals and nerve agents in Guinea pigs.

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Alfred M Sciuto Research Topics

Disease

21	Lung Injury 10/2018 - 07/2004
12	Edema (Dropsy) 01/2017 - 05/2002
10	Body Weight (Weight, Body) 01/2017 - 09/2009
8	Pulmonary Edema 02/2016 - 05/2002
7	Acute Lung Injury 06/2010 - 05/2002
5	Respiratory Insufficiency (Respiratory Failure) 11/2019 - 03/2007
4	Poisoning 01/2019 - 12/2014
4	Inflammation (Inflammations) 06/2014 - 03/2011
3	Necrosis 01/2017 - 05/2002
3	Hemorrhage 01/2017 - 05/2002
2	Weight Loss (Weight Reduction) 01/2017 - 05/2006
2	Tremor (Tremors) 01/2016 - 07/2011
2	Histiocytosis 06/2014 - 12/2013
2	Airway Obstruction (Choking) 06/2003 - 05/2002
1	Acute-Phase Reaction 10/2016
1	Shock 01/2016
1	Cardiotoxicity 01/2016
1	Brain Injuries (Brain Injury) 01/2016
1	Pneumonia (Pneumonitis) 12/2014
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 12/2014
1	Fasciculation (Fasciculations) 09/2013
1	Seizures (Absence Seizure) 07/2008
1	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 05/2007
1	Diarrhea 05/2007
1	Weight Gain 07/2004

Drug/Important Bio-Agent (IBA)

13	Nerve AgentsIBA 01/2016 - 01/2006
9	PhosgeneIBA 01/2017 - 05/2002
7	VX (EDIM)IBA 10/2018 - 01/2006
5	SomanIBA 01/2016 - 06/2010
5	Proteins (Proteins, Gene)FDA Link 07/2008 - 05/2002
4	Cholinergic Agents (Cholinergics)IBA 01/2016 - 03/2011
3	Atropine FDA LinkGeneric 08/2012 - 03/2007
3	SarinIBA 07/2011 - 07/2008
3	Biomarkers (Surrogate Marker)IBA 09/2009 - 06/2006
2	Opioid Analgesics (Opioids)IBA 11/2019 - 01/2017
2	FibrinIBA 01/2017 - 05/2002
2	AmmoniaIBA 01/2017 - 01/2016
2	Cholinesterases (Cholinesterase)IBA 01/2016 - 05/2012
2	Scopolamine (Hyoscine)FDA Link 12/2011 - 07/2011
2	EstersIBA 05/2007 - 05/2006
2	AcidsIBA 05/2007 - 05/2006
2	AntioxidantsIBA 07/2004 - 06/2003
2	Irritants (Vesicants)IBA 06/2003 - 05/2002
1	carfentanil (carfentanyl)IBA 11/2019
1	fluoroacetic acid (sodium fluoroacetate)IBA 01/2019
1	ChloridesIBA 01/2017
1	phosphine (phosphane)IBA 01/2017
1	Naloxone (Narcan)FDA LinkGeneric 01/2017
1	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA 10/2016
1	zymosterolIBA 10/2016
1	Eosine Yellowish-(YS) (Eosin)IBA 01/2016
1	ElectrolytesIBA 01/2016
1	Hematoxylin (Haematoxylon)IBA 01/2016
1	MetalsIBA 01/2016
1	Cholinesterase Inhibitors (Anticholinesterases)IBA 12/2014
1	InsecticidesIBA 12/2014
1	SolventsIBA 12/2014
1	Isoflurophate (DFP)FDA Link 09/2013
1	AcetylcholinesteraseIBA 08/2012
1	N,N'- monomethylenebis(pyridiniumaldoxime)IBA 08/2012
1	OximesIBA 08/2012
1	Cholinergic Antagonists (Anticholinergics)IBA 08/2012
1	p38 Mitogen-Activated Protein KinasesIBA 02/2010
1	Phosphotransferases (Kinase)IBA 02/2010
1	Staphylococcal Protein A (Protein A)IBA 09/2009
1	ButyrylcholinesteraseIBA 06/2006
1	Arachidonic Acid (Vitamin F)IBA 07/2004
1	Glutathione (Reduced Glutathione)IBA 07/2004
1	Free RadicalsIBA 07/2004
1	LeukotrienesIBA 07/2004
1	Biological ProductsIBA 07/2004
1	Indicators and Reagents (Reagents)IBA 06/2003
1	EnzymesIBA 06/2003
1	Coloring Agents (Dyes)IBA 05/2002

Therapy/Procedure

6	Therapeutics 06/2017 - 03/2007